Summary:
- This article presents a comprehensive review of the role of the gut-brain axis in the pathophysiology of Parkinson’s disease, focusing on the bidirectional communication between the gastrointestinal tract and the central nervous system.
- It explores the impact of gut dysbiosis, intestinal permeability, and neuroinflammation on the aggregation of alpha-synuclein, highlighting the potential for gut-targeted therapeutic interventions in neurodegenerative disorders.