Source-Resolved Wastewater Metagenomics Reveals Distinct Resistome and Virulome Landscapes Across an...

TL;DR

Summary:
- This study investigates the prevalence and genomic characteristics of *bla*NDM-1-carrying *Klebsiella pneumoniae* isolates collected from a hospital in China.
- The research utilizes whole-genome sequencing to analyze the dissemination of carbapenem-resistant Enterobacteriaceae (CRE), highlighting the role of IncX3 plasmids in the horizontal transfer of resistance genes.
- The findings emphasize the critical need for robust genomic surveillance and infection control measures to mitigate the clinical threat posed by multi-drug resistant pathogens.

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