Summary:

• **Why Wine Can Give You Headaches**: Wine contains substances called histamines and sulfites that can trigger headaches in some people. When you drink wine, especially red wine, these chemicals can affect your blood vessels and cause pain in your head, similar to how certain foods or allergies affect different people.

• **The Science of Wine Headaches**: Scientists have studied what's in wine to understand why it makes some people's heads hurt. They found that the way grapes are grown, how wine is made, and even the color of the wine can change how many headache-causing chemicals are in each glass.