Summary:
- This article reports on a new gene editing technology called "prime editing" that can precisely insert, delete, or correct genetic sequences without causing unintended changes.
- The researchers demonstrated the versatility of prime editing by using it to correct disease-causing mutations in human cells and to make targeted changes in the genomes of mice, rice, and wheat.
- Prime editing is expected to have significant implications for the treatment of genetic diseases and for advancing genome engineering applications in medicine, agriculture, and basic research.