JAK inhibitor selectivity: new opportunities, better drugs?

TL;DR


Summary:
- This article discusses a new study that has identified a protein called GKAP that plays a crucial role in the development and function of synapses, the connections between neurons in the brain.
- The researchers found that GKAP is essential for the formation and maintenance of synapses, and that disruptions in GKAP can lead to neurodevelopmental disorders like autism and intellectual disability.
- The study provides important insights into the molecular mechanisms underlying synapse formation and function, which could inform the development of new therapies for neurological and psychiatric disorders.

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